The PCM inserts work by either absorbing or releasing thermal energy, helping to keep the temperature inside the pack stable as the temperature outside the pack changes.
The HOT inserts should be used in warmer weather, and should be completely solidified before you leave the house. That way they can absorb the thermal energy that enters the pack, instead of having the epinephrine absorb it. As the inserts absorb incoming heat, they will start to melt, and once the inserts are entirely melted, it’s time to “recharge” them. This can be done by bringing them to a temperature under 82 degrees Fahrenheit (28º C), which should be around room temperature.
The COLD inserts work in the opposite way. They should be entirely liquefied before you leave the house. The COLD inserts will release thermal energy as they freeze due to the colder outside temperature. This helps keep your epinephrine warm. Once the inserts are entirely frozen, you can “recharge” them by bringing them to a temperature above 64 degrees Fahrenheit (18º C), which should be around room temperature.